2. Anti-infection
  3. HBV
  4. 1361030-48-9

1361030-48-9

LDC1267 Chemical Structure

1361030-48-9

Chemical Structure

  • LDC1267
  • CAS No: 1361030-48-9
    Formula: C30H26F2N4O5
    Molecular Weight: 560.55
  • IUPAC Name: N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-3-carboxamide
  • InChIKey: ISPBCAXOSOLFME-UHFFFAOYSA-N
  • SMILES: FC1=CC(NC(C2=NN(C3=CC=C(F)C=C3C)C=C2OCC)=O)=CC=C1OC4=CC=NC5=CC(OC)=C(OC)C=C54
Cat. No. Product Name Purity Description
HY-12494 LDC1267 99.58% LDC1267 is a highly selective TAM (Tyro3, Axl and Mer) kinase inhibitor with IC50s of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively.

References

Paolino M, et al. The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature. 2014 Mar 27;507(7493):508-12. [Content Brief]

Keywords:

LDC1267