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  3. 120042-14-0

120042-14-0

L-Azidohomoalanine Chemical Structure

120042-14-0

Chemical Structure

  • L-Azidohomoalanine
  • CAS No: 120042-14-0
    Formula: C4H8N4O2
    Molecular Weight: 144.13
  • IUPAC Name: (S)-2-amino-4-azidobutanoic acid
  • InChIKey: NNWQLZWAZSJGLY-VKHMYHEASA-N
  • SMILES: O=C(O)[C@@H](N)CCN=[N+]=[N-]

Biological Activity: L-Azidohomoalanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. L-Azidohomoalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description
HY-120059 NS4591 NS4591 is a modulator of calcium-activated potassium channels with activity that enhances small (SK) and intermediate (IK) conductivity. NS4591 doubled IK-mediated currents in whole-cell patch-clamp experiments at a concentration of 45 +/- 6 nM, and doubled SK3-mediated currents at a concentration of 530 +/- 100 nM. NS4591 inhibits the number of action potentials generated by suprathreshold depolarizing pulses in acutely isolated bladder primary afferent neurons. NS4591 also reduced carbakol-induced detrusor ring contraction in the rat bladder, demonstrating sensitivity to apamin.

References

Keywords:

L-Azidohomoalanine