2. Natural Products
  3. Disease Research Fields Plants Ketones, Aldehydes, Acids
  4. Other Diseases Polygalaceae
  5. Polygala hongkongensis Hemsl.
  6. 1269794-89-9

1269794-89-9

GCPII-IN-1 TFA Chemical Structure

1269794-89-9

Chemical Structure

  • GCPII-IN-1 TFA
  • CAS No: 1269794-89-9
    Formula: C14H22F3N3O9
    Molecular Weight: 433.33
  • IUPAC Name: (((S)-5-amino-1-carboxypentyl)carbamoyl)-L-glutamic acid compound with 2,2,2-trifluoroacetic acid (1:1)
  • InChIKey: FNWDAQBGACVZNV-WSZWBAFRSA-N
  • SMILES: OC(C(F)(F)F)=O.NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O

Biological Activity: GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM[1].

Cat. No. Product Name Purity Description
HY-139840A GCPII-IN-1 TFA 99.99% GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM.

References

[1]. Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22(15):4099-108. [Content Brief]

Keywords:

GCPII-IN-1 TFA