2. Autophagy
  3. Autophagy
  4. 1042138-28-2

1042138-28-2

Clionamine B Chemical Structure

1042138-28-2

Chemical Structure

  • Clionamine B
  • CAS No: 1042138-28-2
    Formula: C27H45NO3
    Molecular Weight: 431.65
  • IUPAC Name: (2aS,4S,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-4-amino-9-hydroxy-6a,8a-dimethyl-9-(4-methylpentyl)octadecahydro-10H-naphtho[2',1':4,5]indeno[2,1-b]furan-10-one
  • InChIKey: PLLJOGIAOGXLFM-SIQVBDLFSA-N
  • SMILES: C[C@@]12[C@]3([H])[C@](OC([C@]3(O)CCCC(C)C)=O)([H])C[C@@]1([H])[C@@]4([H])[C@]([C@@]5([C@@](C[C@H](CC5)N)([H])CC4)C)([H])CC2

Biological Activity: Clionamine B is an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Clionamine B strongly stimulates autophagy in human breast cancer MCF-7 cells[1].

Cat. No. Product Name Purity Description
HY-N10305 Clionamine B Clionamine B is an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Clionamine B strongly stimulates autophagy in human breast cancer MCF-7 cells.

References

[1]. Forestieri R, et al. Synthesis of clionamine B, an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Org Lett. 2013;15(15):3918-3921. [Content Brief]

Keywords:

Clionamine B