2. GPCR/G Protein PI3K/Akt/mTOR
  3. Adenosine Receptor PI3K
  4. 104615-18-1

104615-18-1

CGS 15943 Chemical Structure

104615-18-1

Chemical Structure

  • CGS 15943
  • CAS No: 104615-18-1
    Formula: C13H8ClN5O
    Molecular Weight: 285.69
  • IUPAC Name: 9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
  • InChIKey: MSJODEOZODDVGW-UHFFFAOYSA-N
  • SMILES: NC1=NC2=C(C=C(Cl)C=C2)C3=NC(C4=CC=CO4)=NN13

Biological Activity: CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. [1][2].

Cat. No. Product Name Purity Description
HY-100678 CGS 15943 99.96% CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. .

References

[1]. Gao Y, et al. CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil. Life Sci. 1994;55(3):PL61-5. [Content Brief]
[2]. Klotz KN, et al. Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):382-91. [Content Brief]

Keywords:

CGS 15943