2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. 105029-41-2

105029-41-2

Argiotoxin 636 Chemical Structure

105029-41-2

Chemical Structure

  • Argiotoxin 636
  • CAS No: 105029-41-2
    Formula: C29H52N10O6
    Molecular Weight: 636.79
  • InChIKey: FTNICLJXPYLDAH-GOTSBHOMSA-N
  • SMILES: N=C(N)NCCC[C@H](N)C(NCCCNCCCNCCCCCNC([C@H](CC(N)=O)NC(CC1=C(C=C(C=C1)O)O)=O)=O)=O

Biological Activity: Argiotoxin 636 is a toxin and the non-specific, non-competitive, and potent ionotropic glutamate receptor (iGluR) antagonist. Argiotoxin 636 blocks excitatory synaptic transmission in neurons and has paralysis and muscle relaxation effects. Argiotoxin 636 can be used in the study of nervous system diseases[1][2].

Cat. No. Product Name Purity Description
HY-169871 Argiotoxin 636 Argiotoxin 636 is a toxin and the non-specific, non-competitive, and potent ionotropic glutamate receptor (iGluR) antagonist. Argiotoxin 636 blocks excitatory synaptic transmission in neurons and has paralysis and muscle relaxation effects. Argiotoxin 636 can be used in the study of nervous system diseases.

References

[1]. Adams ME, et al. Structures and biological activities of three synaptic antagonists from orb weaver spider venom. Biochem Biophys Res Commun. 1987 Oct 29;148(2):678-83. [Content Brief]
[2]. Ashe JH, et al. Argiotoxin-636 blocks excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons. Brain Res. 1989 Feb 20;480(1-2):234-41. [Content Brief]

Keywords:

Argiotoxin 636