1. Metabolic Enzyme/Protease
  2. Cathepsin
  3. 105637-38-5

105637-38-5

(S,S)-Z-FA-FMK Chemical Structure

105637-38-5

Chemical Structure

  • (S,S)-Z-FA-FMK
  • CAS No: 105637-38-5
    Formula: C21H23FN2O4
    Molecular Weight: 386.42
  • IUPAC Name: benzyl ((S)-1-(((S)-4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
  • InChIKey: ASXVEBPEZMSPHB-YJBOKZPZSA-N
  • SMILES: O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](C)C(CF)=O)=O

Biological Activity: (S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. (S,S)-Z-FA-FMK blocks LPS-induced production of IL-1α and IL-1β. (S,S)-Z-FA-FMK can be used as a negative control for caspase-1 and caspase-2 inhibitors because it lacks an aspartic acid residue at the P1 position[1][2].

Cat. No. Product Name Purity Description
HY-P0109 (S,S)-Z-FA-FMK (S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. (S,S)-Z-FA-FMK blocks LPS-induced production of IL-1α and IL-1β. (S,S)-Z-FA-FMK can be used as a negative control for caspase-1 and caspase-2 inhibitors because it lacks an aspartic acid residue at the P1 position.

References

Keywords:

(S,S)-Z-FA-FMK