2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. 105878-43-1

105878-43-1

Bisoprolol fumarate Chemical Structure

105878-43-1

Chemical Structure

  • Bisoprolol fumarate
  • CAS No: 105878-43-1
    Formula: C22H35NO8
    Molecular Weight: 441.52
  • IUPAC Name: 1-(4-((2-isopropoxyethoxy)methyl)phenoxy)-3-(isopropylamino)propan-2-ol fumarate
  • InChIKey: RZPZLFIUFMNCLY-WLHGVMLRSA-N
  • SMILES: OC(COC1=CC=C(C=C1)COCCOC(C)C)CNC(C)C.OC(/C=C/C(O)=O)=O

Biological Activity: Bisoprolol fumarate is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol fumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2].

Cat. No. Product Name Purity Description
HY-120829 Bisoprolol fumarate Bisoprolol fumarate is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol fumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research.
HY-120829S Bisoprolol-d5 hemifumarate Bisoprolol-d5 (hemifumarate) is deuterium labeled Bisoprolol (fumarate).

References

[1]. Jillian G Baker, et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22. [Content Brief]
[2]. Jing Wang, et al. Bisoprolol, a β 1 antagonist, protects myocardial cells from ischemia-reperfusion injury via PI3K/AKT/GSK3β pathway. Fundam Clin Pharmacol. 2020 Dec;34(6):708-720. [Content Brief]

Keywords:

Bisoprolol fumarateBisoprolol-d5 hemifumarate