2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphatase
  4. 171506-87-9

171506-87-9

T16A(inh)-C01 Chemical Structure

171506-87-9

Chemical Structure

  • T16A(inh)-C01
  • CAS No: 171506-87-9
    Formula: C18H16O5
    Molecular Weight: 312.32
  • IUPAC Name: ethyl 5-hydroxy-2-(phenoxymethyl)benzofuran-3-carboxylate
  • InChIKey: WMKWHWVWSKDZQK-UHFFFAOYSA-N
  • SMILES: O=C(OCC)C1=C(OC2=CC=C(C=C12)O)COC3=CC=CC=C3

Biological Activity: T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].

Cat. No. Product Name Purity Description
HY-118170 T16A(inh)-C01 90 T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling.

References

[1]. Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286(3):2365-74. [Content Brief]

Keywords:

T16A(inh)-C01