1. Protein Tyrosine Kinase/RTK Anti-infection Autophagy
  2. Bcr-Abl PDGFR c-Kit SARS-CoV Autophagy
  3. 1808260-45-8

1808260-45-8

ML356 Chemical Structure

1808260-45-8

Chemical Structure

  • ML356
  • CAS No: 1808260-45-8
    Formula: C19H25N3O4S2
    Molecular Weight: 423.55
  • IUPAC Name: 2-ethyl-N-(4-(4-(morpholinosulfonyl)phenyl)thiazol-2-yl)butanamide
  • InChIKey: YKNITTNJEATJKT-UHFFFAOYSA-N
  • SMILES: O=C(C(CC)CC)NC1=NC(C2=CC=C(S(=O)(N3CCOCC3)=O)C=C2)=CS1

Biological Activity: ML356 (Compound 16) is an inhibitor for fatty acid synthase (FAS), that inhibits the thioesterase domain of FAS (FAS TE) with an IC50 of 0.334 μM, and blocks the de novo palmitate synthesis in PC-3 cell with an IC50 of 20 μM. ML356 exhibits good membrane permeability, and good stability in human and mouse plasma[1].

Cat. No. Product Name Purity Description
HY-118147 ML356 ML356 (Compound 16) is an inhibitor for fatty acid synthase (FAS), that inhibits the thioesterase domain of FAS (FAS TE) with an IC50 of 0.334 μM, and blocks the de novo palmitate synthesis in PC-3 cell with an IC50 of 20 μM. ML356 exhibits good membrane permeability, and good stability in human and mouse plasma.

References

Keywords:

ML356