2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Apoptosis
  3. EGFR Apoptosis
  4. 1821293-40-6

1821293-40-6

Sutidiazine Chemical Structure

1821293-40-6

Chemical Structure

  • Sutidiazine
  • Synonym(s): ZY-19489; MMV 253; AZ13721412
  • CAS No: 1821293-40-6
    Formula: C24H32FN9
    Molecular Weight: 465.57
  • IUPAC Name: (R)-N2-(4-cyclopropyl-5-fluoro-6-methylpyridin-2-yl)-N4-(1,5-dimethyl-1H-pyrazol-3-yl)-5-(3,4-dimethylpiperazin-1-yl)pyrimidine-2,4-diamine
  • InChIKey: HKPQFVAUXAZCDY-OAHLLOKOSA-N
  • SMILES: CC1=CC(NC2=NC(NC3=NC(C)=C(F)C(C4CC4)=C3)=NC=C2N5C[C@@H](C)N(C)CC5)=NN1C

Biological Activity: Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect[1].

Cat. No. Product Name Purity Description
HY-148177 Sutidiazine Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect.

References

[1]. Ghoghari AM, et al. Simultaneous estimation of ZY-19489 and its active metabolite ZY-20486 in human plasma using LC-MS/MS, a novel antimalarial compound. Bioanalysis. 2021 Dec;13(23):1761-1777. [Content Brief]

Keywords:

Sutidiazine