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  6. 278605-15-5

278605-15-5

p-Ethynylphenylalanine Chemical Structure

278605-15-5

Chemical Structure

  • p-Ethynylphenylalanine
  • Synonym(s): 4-Ethynyl-L-phenylalanine
  • CAS No: 278605-15-5
    Formula: C11H11NO2
    Molecular Weight: 189.21
  • IUPAC Name: (S)-2-amino-3-(4-ethynylphenyl)propanoic acid
  • InChIKey: PPDNGMUGVMESGE-JTQLQIEISA-N
  • SMILES: N[C@@H](CC1=CC=C(C#C)C=C1)C(O)=O

Biological Activity: p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM[1]. p-Ethynylphenylalanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No. Product Name Purity Description
HY-23460 p-Ethynylphenylalanine 99.93% p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM. p-Ethynylphenylalanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1]. Stokes AH, et al. p-ethynylphenylalanine: a potent inhibitor of tryptophan hydroxylase. J Neurochem. 2000 May;74(5):2067-73. [Content Brief]

Keywords:

p-Ethynylphenylalanine