2. Cell Cycle/DNA Damage Cytoskeleton
  3. Mps1
  4. 1125593-20-5

1125593-20-5

Mps1-IN-1 Chemical Structure

1125593-20-5

Chemical Structure

  • Mps1-IN-1
  • CAS No: 1125593-20-5
    Formula: C28H33N5O4S
    Molecular Weight: 535.66
  • IUPAC Name: 1-(4-((4-((2-(isopropylsulfonyl)phenyl)amino)-1H-pyrrolo[2,3-b]pyridin-6-yl)amino)-3-methoxyphenyl)piperidin-4-ol
  • InChIKey: NMJMRSQTDLRCRQ-UHFFFAOYSA-N
  • SMILES: O=S(C(C=CC=C1)=C1NC2=CC(NC3=C(OC)C=C(N4CCC(O)CC4)C=C3)=NC5=C2C=CN5)(C(C)C)=O

Biological Activity: Mps1-IN-1 is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 367 nM and 27 nM[1].

Cat. No. Product Name Purity Description
HY-13298 Mps1-IN-1 99.77% Mps1-IN-1 is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 367 nM and 27 nM.

References

[1]. Kwiatkowski N, et al. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010 May;6(5):359-68. [Content Brief]

Keywords:

Mps1-IN-1