1. Others Vitamin D Related/Nuclear Receptor
  2. Isotope-Labeled Compounds Estrogen Receptor/ERR
  3. 142808-44-4

142808-44-4

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite Chemical Structure

142808-44-4

Chemical Structure

  • 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
  • CAS No: 142808-44-4
    Formula: C46H50F2N5O8P
    Molecular Weight: 869.89
  • IUPAC Name: (2R,3R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4,4-difluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • InChIKey: XLVPZSDAOMSDQP-XBADOKRKSA-N
  • SMILES: CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C(F)(F)[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

Biological Activity: 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cat. No. Product Name Purity Description
HY-154222 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

References