1. Metabolic Enzyme/Protease Neuronal Signaling
  2. FAAH
  3. 1143578-94-2

1143578-94-2

FAAH-IN-6 Chemical Structure

1143578-94-2

Chemical Structure

  • FAAH-IN-6
  • CAS No: 1143578-94-2
    Formula: C19H17F2N7O
    Molecular Weight: 397.38
  • IUPAC Name: 4-(4-(3,4-difluorophenyl)pyrimidin-2-yl)-N-(pyridazin-3-yl)piperazine-1-carboxamide
  • InChIKey: JCWVFSJNIBAGQN-UHFFFAOYSA-N
  • SMILES: O=C(N1CCN(C2=NC=CC(C3=CC=C(F)C(F)=C3)=N2)CC1)NC4=NN=CC=C4

Biological Activity: FAAH-IN-6 (compound 21d) is a potent, orally active and cross the blood-brain barrier fatty acid amide hydrolase (FAAH) inhibitor with IC50s of 0.72, 0.28 nM for hFAAH, rFAAH, respectively. FAAH-IN-6 shows dose-dependent analgesic efficacy in animal models of both neuropathic and inflammatory pain[1].

Cat. No. Product Name Purity Description
HY-103461 FAAH-IN-6 99.70% FAAH-IN-6 (compound 21d) is a potent, orally active and cross the blood-brain barrier fatty acid amide hydrolase (FAAH) inhibitor with IC50s of 0.72, 0.28 nM for hFAAH, rFAAH, respectively. FAAH-IN-6 shows dose-dependent analgesic efficacy in animal models of both neuropathic and inflammatory pain.

References

Keywords:

FAAH-IN-6