1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. 1161205-04-4

1161205-04-4

VU0361737 Chemical Structure

1161205-04-4

Chemical Structure

  • VU0361737
  • Synonym(s): ML-128
  • CAS No: 1161205-04-4
    Formula: C13H11ClN2O2
    Molecular Weight: 262.69
  • IUPAC Name: N-(4-chloro-3-methoxyphenyl)picolinamide
  • InChIKey: ARYUXFNGXHNNDM-UHFFFAOYSA-N
  • SMILES: ClC(C=C1)=C(OC)C=C1NC(C2=NC=CC=C2)=O

Biological Activity: VU0361737 (ML-128) is a potent, selective and CNS penetrant positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4 PAM), with EC50s of 240 nM and 110 nM for human and rat mGluR4 receptors, respectively. VU0361737 has neuroprotective effect. VU0361737 is potential for Parkinson's disease research[1][2].

Cat. No. Product Name Purity Description
HY-W009412S D-Phenyl-alanine-N-t-Boc-d5 99.85% D-Phenyl-alanine-N-t-Boc-d5 is the deuterium labeled D-Phenyl-alanine-N-t-Boc.
HY-W009412 Boc-D-Phe-OH ≥98.0% Boc-D-Phe-OH is a phenylalanine derivative.

References

Keywords:

VU0361737