2. PROTAC
  3. PROTAC Linkers
  4. 1198080-04-4

1198080-04-4

Propargyl-PEG6-NH2 Chemical Structure

1198080-04-4

Chemical Structure

  • Propargyl-PEG6-NH2
  • CAS No: 1198080-04-4
    Formula: C15H29NO6
    Molecular Weight: 319.39
  • IUPAC Name: 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-amine
  • InChIKey: USTJDUXGVRIRRT-UHFFFAOYSA-N
  • SMILES: C#CCOCCOCCOCCOCCOCCOCCN

Biological Activity: Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No. Product Name Purity Description
HY-130180 Propargyl-PEG6-NH2 99.69% Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]

Keywords:

Propargyl-PEG6-NH2