2. Cell Cycle/DNA Damage Apoptosis
  3. Checkpoint Kinase (Chk) Apoptosis
  4. 3022924-04-2

3022924-04-2

ZIKV-IN-8 Chemical Structure

3022924-04-2

Chemical Structure

  • ZIKV-IN-8
  • CAS No: 3022924-04-2
    Formula: C21H19N5O4
    Molecular Weight: 405.41
  • InChIKey: CCCBTLHGSDPCPB-UHFFFAOYSA-N
  • SMILES: CC1=C(C(C2=O)=NN1C3=CC=C(OC)C=C3)C(C)=NN2CC4=CC([N+]([O-])=O)=CC=C4

Biological Activity: ZIKV-IN-8 (Compound 9b) is a noncompetitive Zika virus (ZIKV) inhibitor. ZIKV-IN-8 shows the best anti-ZIKV activity with a selectivity index of 22.4. ZIKV-IN-8 has significant inhibition of ZIKV with an IC50 value of 25.6 μM. ZIKV-IN-8 can be used for the research of ZIKV infection[1].

Cat. No. Product Name Purity Description
HY-162073 ZIKV-IN-8 ZIKV-IN-8 (Compound 9b) is a noncompetitive Zika virus (ZIKV) inhibitor. ZIKV-IN-8 shows the best anti-ZIKV activity with a selectivity index of 22.4. ZIKV-IN-8 has significant inhibition of ZIKV with an IC50 value of 25.6 μM. ZIKV-IN-8 can be used for the research of ZIKV infection.

References

[1]. Quang De Tran, et al. ZIKV Inhibitors Based on Pyrazolo[3,4-d]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies. ACS Omega 2023 8 (51), 48994-49008

Keywords:

ZIKV-IN-8