2. Cell Cycle/DNA Damage Epigenetics Apoptosis
  3. HDAC Apoptosis
  4. 2769753-49-1

2769753-49-1

FLT3 Ligand-Linker Conjugate 1 Chemical Structure

2769753-49-1

Chemical Structure

  • FLT3 Ligand-Linker Conjugate 1
  • CAS No: 2769753-49-1
    Formula: C29H34N6O4S2
    Molecular Weight: 594.75
  • SMILES: CS(NC1=CC=CC(C2=CSC3=CN=C(N=C23)NC4=CC=C(N5CCN(CC5)CCCCCC(O)=O)C=C4)=C1)(=O)=O

Biological Activity: FLT3 Ligand-Linker Conjugate 1 (compound 7) contains the FLT3 ligand and a PROTAC linker, which can recruit the E3 ligase VHL. FLT3 Ligand-Linker Conjugate 1 can be used to synthesize the PROTAC RSS0680 (HY-148062). PROTAC RSS0680 is a bifunctional compound that targets protein degradation of kinases[1].

Cat. No. Product Name Purity Description
HY-170769 FLT3 Ligand-Linker Conjugate 1 FLT3 Ligand-Linker Conjugate 1 (compound 7) contains the FLT3 ligand and a PROTAC linker, which can recruit the E3 ligase VHL. FLT3 Ligand-Linker Conjugate 1 can be used to synthesize the PROTAC RSS0680 (HY-148062). PROTAC RSS0680 is a bifunctional compound that targets protein degradation of kinases.

References

[1]. Gray Nathanael S, et al. Bifunctional compounds for targeted protein degradation of kinases: World Intellectual Property Organization, WO2022093742[P]. 2022-05-05.

Keywords:

FLT3 Ligand-Linker Conjugate 1