2. Anti-infection
  3. Bacterial
  4. 127142-14-7

127142-14-7

BW 348U87 Chemical Structure

127142-14-7

Chemical Structure

  • BW 348U87
  • Synonym(s): 348U87
  • CAS No: 127142-14-7
    Formula: C15H15ClN6S2
    Molecular Weight: 378.90
  • IUPAC Name: (E)-N-(2-chlorophenyl)-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazine-1-carbonothioyl)hydrazine-1-carbothioamide
  • InChIKey: YYLKOELWSMRYHV-VXLYETTFSA-N
  • SMILES: C/C(C1=CC=CC=N1)=N\NC(NNC(NC2=C(C=CC=C2)Cl)=S)=S

Biological Activity: BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model[1].

Cat. No. Product Name Purity Description
HY-106892 BW 348U87 99.62% BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model.

References

[1]. Spector T, et al., Inactivators of herpes simplex virus ribonucleotide reductase: hematological profiles and in vivo potentiation of the antiviral activity of acyclovir. Antimicrob Agents Chemother. 1992 May;36(5):934-7. [Content Brief]

Keywords:

BW 348U87