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  5. 53330-02-2

53330-02-2

S-(N-PhenethylthiocarbaMoyl)-L-cysteine Chemical Structure

53330-02-2

Chemical Structure

  • S-(N-PhenethylthiocarbaMoyl)-L-cysteine
  • Synonym(s): PEITC-Cys
  • CAS No: 53330-02-2
    Formula: C12H16N2O2S2
    Molecular Weight: 284.40
  • IUPAC Name: S-(phenethylcarbamothioyl)-L-cysteine
  • InChIKey: FWNOABWJBHBVKJ-JTQLQIEISA-N
  • SMILES: N[C@@H](CSC(NCCC1=CC=CC=C1)=S)C(O)=O

Biological Activity: S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor[2].

Cat. No. Product Name Purity Description
HY-115754 S-(N-PhenethylthiocarbaMoyl)-L-cysteine S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor.

References

[1]. Adesida A, Edwards LG, Thornalley PJ. Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate. Food Chem Toxicol. 1996 Apr;34(4):385-92. [Content Brief]
[2]. Conaway CC, et al. Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes. Chem Res Toxicol. 2001 Sep;14(9):1170-6. [Content Brief]

Keywords:

S-(N-PhenethylthiocarbaMoyl)-L-cysteine