2. PROTAC
  3. PROTAC Linkers
  4. 1310827-26-9

1310827-26-9

S-Acetyl-PEG3-azide Chemical Structure

1310827-26-9

Chemical Structure

  • S-Acetyl-PEG3-azide
  • CAS No: 1310827-26-9
    Formula: C10H19N3O4S
    Molecular Weight: 277.34
  • IUPAC Name: S-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl) ethanethioate
  • InChIKey: PIXCCFAIMVRUDJ-UHFFFAOYSA-N
  • SMILES: CC(SCCOCCOCCOCCN=[N+]=[N-])=O

Biological Activity: S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. S-Acetyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description
HY-140859 S-Acetyl-PEG3-azide S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. S-Acetyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Keywords:

S-Acetyl-PEG3-azide