2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. 1835759-71-1

1835759-71-1

Azido-PEG4-(CH2)3-methyl ester Chemical Structure

1835759-71-1

Chemical Structure

  • Azido-PEG4-(CH2)3-methyl ester
  • CAS No: 1835759-71-1
    Formula: C13H25N3O6
    Molecular Weight: 319.35
  • IUPAC Name: methyl 1-azido-3,6,9,12-tetraoxahexadecan-16-oate
  • InChIKey: PZVGELSZWFBVCY-UHFFFAOYSA-N
  • SMILES: O=C(OC)CCCOCCOCCOCCOCCN=[N+]=[N-]

Biological Activity: Azido-PEG4-(CH2)3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-(CH2)3-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description
HY-140854 Azido-PEG4-(CH2)3-methyl ester Azido-PEG4-(CH2)3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG4-(CH2)3-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Keywords:

Azido-PEG4-(CH2)3-methyl ester