2. Cell Cycle/DNA Damage Others Cytoskeleton
  3. Drug Intermediate Microtubule/Tubulin
  4. 215312-86-0

215312-86-0

6-Maleimidocaproic acid sulfo-NHS sodium Chemical Structure

215312-86-0

Chemical Structure

  • 6-Maleimidocaproic acid sulfo-NHS sodium
  • Synonym(s): Sulfo-EMCS
  • CAS No: 215312-86-0
    Formula: C14H15N2NaO9S
    Molecular Weight: 410.33
  • IUPAC Name: sodium 1-((6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate
  • InChIKey: MIDXXTLMKGZDPV-UHFFFAOYSA-M
  • SMILES: O=C(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)CCCCCN2C(C=CC2=O)=O

Biological Activity: 6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Cat. No. Product Name Purity Description
HY-136158A 6-Maleimidocaproic acid sulfo-NHS sodium 98.91% 6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Keywords:

6-Maleimidocaproic acid sulfo-NHS sodium