2. GPCR/G Protein
  3. LPL Receptor
  4. 1355026-60-6

1355026-60-6

CYM50260 Chemical Structure

1355026-60-6

Chemical Structure

  • CYM50260
  • CAS No: 1355026-60-6
    Formula: C14H11Cl3FNO2
    Molecular Weight: 350.60
  • IUPAC Name: 2-chloro-3-(2-(2,4-dichlorophenoxy)ethoxy)-6-(fluoromethyl)pyridine
  • InChIKey: FHPOTBQOUBMMCI-UHFFFAOYSA-N
  • SMILES: FCC1=CC=C(OCCOC2=CC=C(Cl)C=C2Cl)C(Cl)=N1

Biological Activity: CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R[1].

Cat. No. Product Name Purity Description
HY-108494 CYM50260 99.70% CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.

References

[1]. Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42. [Content Brief]

Keywords:

CYM50260