2. Epigenetics TGF-beta/Smad
  3. PKC
  4. 544686-20-6

544686-20-6

Celecoxib-d<sub>4</sub> Chemical Structure

544686-20-6

Chemical Structure

  • Celecoxib-d4
  • CAS No: 544686-20-6
    Formula: C17H10D4F3N3O2S
    Molecular Weight: 385.40
  • IUPAC Name: 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzene-2,3,5,6-d4-sulfonamide
  • InChIKey: RZEKVGVHFLEQIL-YKVCKAMESA-N
  • SMILES: FC(F)(C1=NN(C2=C([2H])C([2H])=C(C([2H])=C2[2H])S(N)(=O)=O)C(C3=CC=C(C=C3)C)=C1)F

Biological Activity: Celecoxib-d4 is the deuterium labeled Desmethyl Celecoxib. Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%[1].

Cat. No. Product Name Purity Description
HY-130356 5-trans U-46619 5-trans U-46619 is a PGE synthase inhibitor. At a concentration of 10 μM, 5-trans U-46619 inhibits PGE synthase by <20%.

Keywords:

Celecoxib-d4Celecoxib-d3Celecoxib-d7CelecoxibCelecoxib (Standard)Celecoxib (GMP Like)Celecoxib (GMP)