2. Neuronal Signaling
  3. Sigma Receptor
  4. 174635-69-9

174635-69-9

SB-222200 Chemical Structure

174635-69-9

Chemical Structure

  • SB-222200
  • CAS No: 174635-69-9
    Formula: C26H24N2O
    Molecular Weight: 380.48
  • IUPAC Name: (S)-3-methyl-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
  • InChIKey: MQNYRKWJSMQECI-QFIPXVFZSA-N
  • SMILES: O=C(C1=C(C)C(C2=CC=CC=C2)=NC3=CC=CC=C13)N[C@H](C4=CC=CC=C4)CC

Biological Activity: SB-222200 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant NK-3 receptor antagonist. SB-222200 is developed for central nervous system (CNS) disorders[1].

Cat. No. Product Name Purity Description
HY-15722 SB-222200 99.85% SB-222200 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant NK-3 receptor antagonist. SB-222200 is developed for central nervous system (CNS) disorders.

References

[1]. Sarau HM, et al. Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist. J Pharmacol Exp Ther. 2000 Oct;295(1):373-81. [Content Brief]

Keywords:

SB-222200