2. Cell Cycle/DNA Damage
  3. Eukaryotic Initiation Factor (eIF)
  4. 1401034-19-2

1401034-19-2

AMG 925 (HCl) Chemical Structure

1401034-19-2

Chemical Structure

  • AMG 925 (HCl)
  • CAS No: 1401034-19-2
    Formula: C26H30ClN7O2
    Molecular Weight: 508.02
  • IUPAC Name: 2-hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethan-1-one hydrochloride
  • InChIKey: JJDSFFVYZSLRLY-AELULUIVSA-N
  • SMILES: OCC(N1CC2=C(N=C(NC3=NC=C4C(N([C@H]5CC[C@H](C)CC5)C6=CN=CC=C64)=N3)C=C2)CC1)=O.Cl

Biological Activity: AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively.

Cat. No. Product Name Purity Description
HY-15889A AMG 925 (HCl) AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively.

Keywords:

AMG 925 (HCl)