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2866299-06-9

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Chemical Structure

2866299-06-9

Chemical Structure

  • Exatecan-amide-bicyclo[1.1.1]pentan-1-ol
  • CAS No: 2866299-06-9
    Formula: C30H28FN3O6
    Molecular Weight: 545.56
  • InChIKey: CMOSLGSHFWDOOX-QKZKXOKASA-N
  • SMILES: O=C(C12CC(C1)(C2)O)N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84

Biological Activity: Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines[1].

Cat. No. Product Name Purity Description
HY-160597 Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines.

References

[1]. VRLJIC M, et al. Exatecan derivatives and antibody-drug conjugates thereof. WO2022236136A1. 2022-11-10.

Keywords:

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol