2. Others Metabolic Enzyme/Protease
  3. Biochemical Assay Reagents Endogenous Metabolite
  4. 3032670-12-2

3032670-12-2

Mz325 Chemical Structure

3032670-12-2

Chemical Structure

  • Mz325
  • CAS No: 3032670-12-2
    Formula: C38H45N9O5S2
    Molecular Weight: 771.95
  • InChIKey: VNFKTHQLIBPFNF-UHFFFAOYSA-N
  • SMILES: O=C(NC1=NC=C(S1)CC2=CC=CC(OCC3=CN(N=N3)CCCCC(N(CC4=CC=C(C=C4)C(NO)=O)CCCC)=O)=C2)CSC5=NC(C)=CC(C)=N5

Biological Activity: Mz325 is a dual inhibitor of HDAC and Sirt2, with the IC50 of 9.7 μM to Sirt2, that play an important role in pathogenesis of cancer and neurodegeneration[1].

Cat. No. Product Name Purity Description
HY-155392 Mz325 Mz325 is a dual inhibitor of HDAC and Sirt2, with the IC50 of 9.7 μM to Sirt2, that play an important role in pathogenesis of cancer and neurodegeneration.

References

[1]. Laura Sinatra, et al. Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J Med Chem. 2023 Nov 9;66(21):14787-14814. [Content Brief]

Keywords:

Mz325