2. Metabolic Enzyme/Protease
  3. HIF/HIF Prolyl-Hydroxylase
  4. 2095128-20-2

2095128-20-2

Bocidelpar Chemical Structure

2095128-20-2

Chemical Structure

  • Bocidelpar
  • Synonym(s): ASP0367; MA-0211
  • CAS No: 2095128-20-2
    Formula: C25H27F3N2O3
    Molecular Weight: 460.49
  • IUPAC Name: (R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoic acid
  • InChIKey: FMOPHFSPINWSOV-QGZVFWFLSA-N
  • SMILES: O=C(O)C[C@H](C)CCCOC1=CC=CC=C1CN2C(C)=CN=C2C3=CC=C(C(F)(F)F)C=C3

Biological Activity: Bocidelpar is a modulator of peroxisome proliferator-activated receptor delta (PPAR-δ). Bocidelpar improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy (DMD) muscle cells[1][2].

Cat. No. Product Name Purity Description
HY-134377 Bocidelpar 98.08% Bocidelpar is a modulator of peroxisome proliferator-activated receptor delta (PPAR-δ). Bocidelpar improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy (DMD) muscle cells.

References

[1]. Michael Downes, et al. Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof. Patent WO2017062468A1.
[2]. Ito M, et al. Single- and multiple-dose safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of ASP0367, or bocidelpar sulfate, a novel modulator of peroxisome proliferator-activated receptor delta in healthy adults: Results from a phase 1 study. Muscle Nerve. 2022 Jan;65(1):110-120. [Content Brief]

Keywords:

Bocidelpar