2. GPCR/G Protein
  3. Free Fatty Acid Receptor
  4. 2411681-92-8

2411681-92-8

Desthiobiotin-PEG3-NHS ester Chemical Structure

2411681-92-8

Chemical Structure

  • Desthiobiotin-PEG3-NHS ester
  • CAS No: 2411681-92-8
    Formula: C23H38N4O9
    Molecular Weight: 514.57
  • IUPAC Name: 2,5-dioxopyrrolidin-1-yl 19-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)-14-oxo-4,7,10-trioxa-13-azanonadecanoate
  • InChIKey: JWHMGEZINQQWSX-ZWKOTPCHSA-N
  • SMILES: O=C(N[C@H]1C)N[C@@H]1CCCCCC(NCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O)=O

Biological Activity: Desthiobiotin-PEG3-NHS ester is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin.

Keywords:

Desthiobiotin-PEG3-NHS ester