1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  2. EGFR
  3. 1423077-49-9

1423077-49-9

RTC-5 Chemical Structure

1423077-49-9

Chemical Structure

  • RTC-5
  • Synonym(s): TRC-382
  • CAS No: 1423077-49-9
    Formula: C24H22ClF3N2O3S
    Molecular Weight: 510.96
  • IUPAC Name: N-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide
  • InChIKey: QYOJMNDDVVEPFN-UHFFFAOYSA-N
  • SMILES: O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O

Biological Activity: RTC-5 (TRC-382) is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling[1].

Cat. No. Product Name Purity Description
HY-123952 RTC-5 99.89% RTC-5 (TRC-382) is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling.

References

Keywords:

RTC-5