2. Metabolic Enzyme/Protease
  3. Proteasome
  4. 1446350-60-2

1446350-60-2

TCH-165 Chemical Structure

1446350-60-2

Chemical Structure

  • TCH-165
  • CAS No: 1446350-60-2
    Formula: C39H37N3O3
    Molecular Weight: 595.73
  • IUPAC Name: ethyl (4R,5R)-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate
  • InChIKey: XXDLWRCUPASJGY-AEGYFVCZSA-N
  • SMILES: O=C([C@]1(C2=CC=CC=C2)N=C(C3=CC=C(OC)C=C3)N(CC4=CC=CC=C4)[C@@H]1C5=CC=C(NCC6=CC=CC=C6)C=C5)OCC

Biological Activity: TCH-165 is a small molecule modulator of proteasome assembly, which increases 20S levels and facilitates 20S-mediated protein degradation[1].

Cat. No. Product Name Purity Description
HY-120722 TCH-165 99.32% TCH-165 is a small molecule modulator of proteasome assembly, which increases 20S levels and facilitates 20S-mediated protein degradation.

References

[1]. Njomen E, et al. Small Molecule Modulation of Proteasome Assembly. Biochemistry. 2018 Jul 17;57(28):4214-4224. [Content Brief]

Keywords:

TCH-165