1. Cell Cycle/DNA Damage
  2. Eukaryotic Initiation Factor (eIF)
  3. 1448693-69-3

1448693-69-3

GCN2-IN-1 Chemical Structure

1448693-69-3

Chemical Structure

  • GCN2-IN-1
  • Synonym(s): A-92
  • CAS No: 1448693-69-3
    Formula: C19H18N10O
    Molecular Weight: 402.41
  • IUPAC Name: 3-(1H-indazol-6-yl)-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
  • InChIKey: CFNFLNGJQOHNPR-UHFFFAOYSA-N
  • SMILES: C1(NC2=CN(C3CCOCC3)N=C2)=NC=C(N=NN4C5=CC6=C(C=C5)C=NN6)C4=N1

Biological Activity: GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 μM in the enzyme assay and an IC50 of 0.3-3 μM in the cell assay[1].

Cat. No. Product Name Purity Description
HY-100877 GCN2-IN-1 ≥98.0% GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 μM in the enzyme assay and an IC50 of 0.3-3 μM in the cell assay.

References

Keywords:

GCN2-IN-1