1. Apoptosis
  2. MDM-2/p53
  3. 1448867-42-2

1448867-42-2

Siremadlin (R Enantiomer) Chemical Structure

1448867-42-2

Chemical Structure

  • Siremadlin (R Enantiomer)
  • Synonym(s): NVP-HDM201 (R Enantiomer); HDM201 (R Enantiomer)
  • CAS No: 1448867-42-2
    Formula: C26H24Cl2N6O4
    Molecular Weight: 555.41
  • IUPAC Name: (R)-5-(5-chloro-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-1-isopropyl-5,6-dihydropyrrolo[3,4-d]imidazol-4(1H)-one
  • InChIKey: AGBSXNCBIWWLHD-HXUWFJFHSA-N
  • SMILES: O=C1N(C2=CC(Cl)=CN(C)C2=O)[C@H](C3=CC=C(Cl)C=C3)C4=C1N=C(C5=CN=C(OC)N=C5OC)N4C(C)C

Biological Activity: Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.

Cat. No. Product Name Purity Description
HY-18658A Siremadlin (R Enantiomer) 99.12% Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.