2. Protein Tyrosine Kinase/RTK Apoptosis
  3. Anaplastic lymphoma kinase (ALK) ROS Kinase Apoptosis
  4. 2720615-82-5

2720615-82-5

Azido-PEG4-Thiol Chemical Structure

2720615-82-5

Chemical Structure

  • Azido-PEG4-Thiol
  • CAS No: 2720615-82-5
    Formula: C10H21N3O4S
    Molecular Weight: 279.36
  • IUPAC Name: 14-azido-3,6,9,12-tetraoxatetradecane-1-thiol
  • InChIKey: WXJHTWKPNRQSLU-UHFFFAOYSA-N
  • SMILES: SCCOCCOCCOCCOCCN=[N+]=[N-]

Biological Activity: Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description
HY-138525 Azido-PEG4-Thiol Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Keywords:

Azido-PEG4-Thiol