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357166-30-4

Pemetrexed disodium hemipenta hydrate Chemical Structure

357166-30-4

Chemical Structure

  • Pemetrexed disodium hemipenta hydrate
  • Synonym(s): LY231514 disodium hemipenta hydrate
  • CAS No: 357166-30-4
    Formula: C20H24N5Na2O8.5
    Molecular Weight: 516.41
  • SMILES: O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(CCC2=CNC(N=C(N)N3)=C2C3=O)C=C1)=O.[2.5H2O]

Biological Activity: Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

Cat. No. Product Name Purity Description
HY-13781 Pemetrexed disodium hemipenta hydrate 99.78% Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.