2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. 2913165-27-0

2913165-27-0

E3 ligase Ligand 59 Chemical Structure

2913165-27-0

Chemical Structure

  • E3 ligase Ligand 59
  • CAS No: 2913165-27-0
    Formula: C17H21N3O3
    Molecular Weight: 315.37
  • InChIKey: WADKPYKRCZQBSV-UHFFFAOYSA-N
  • SMILES: O=C1CCC(C2=CN=C(N3CCC(CC=O)CC3)C=C2)C(N1)=O

Biological Activity: E3 ligase Ligand 59 (Compound 20e) is the E3 ubiquitin ligase ligand of FDU73 (HY-173125). E3 ligase Ligand 59 can be used to synthesize PROTACs[1].

Cat. No. Product Name Purity Description
HY-173378 E3 ligase Ligand 59 E3 ligase Ligand 59 (Compound 20e) is the E3 ubiquitin ligase ligand of FDU73 (HY-173125). E3 ligase Ligand 59 can be used to synthesize PROTACs.

References

[1]. Lin Y, et al. Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties. Eur J Med Chem. 2025 May 5;289:117420. [Content Brief]

Keywords:

E3 ligase Ligand 59