2. Immunology/Inflammation PI3K/Akt/mTOR Epigenetics Metabolic Enzyme/Protease NF-κB MAPK/ERK Pathway Apoptosis
  3. NOD-like Receptor (NLR) Interleukin Related AMPK Reactive Oxygen Species Toll-like Receptor (TLR) NF-κB JNK p38 MAPK Apoptosis
  4. 2085274-00-4

2085274-00-4

Antifungal agent 35 Chemical Structure

2085274-00-4

Chemical Structure

  • Antifungal agent 35
  • CAS No: 2085274-00-4
    Formula: C26H27BrN4O4
    Molecular Weight: 539.42
  • IUPAC Name: 3-(4-bromo-2-methoxyphenyl)-N-(2-((2-(cyclohex-1-en-1-yl)ethyl)amino)-2-oxoethyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide
  • InChIKey: RGMIHEWYUXSZJY-UHFFFAOYSA-N
  • SMILES: O=C(C1=NN(C2=CC=C(C=C2OC)Br)C(C3=C1C=CC=C3)=O)NCC(NCCC4=CCCCC4)=O

Biological Activity: Antifungal agent 35 (compound 24) is a potent antifungal agent. Antifungal agent 35 is a potent enhancer of antifungal activity of Fluconazole against C. albicans[1].

Cat. No. Product Name Purity Description
HY-147238 Antifungal agent 35 Antifungal agent 35 (compound 24) is a potent antifungal agent. Antifungal agent 35 is a potent enhancer of antifungal activity of Fluconazole against C. albicans.

References

[1]. Mood AD, et, al. Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans. ACS Med Chem Lett. 2017 Jan 11;8(2):168-173. [Content Brief]

Keywords:

Antifungal agent 35