2. Anti-infection
  3. Bacterial
  4. 375822-19-8

375822-19-8

D-Ala-Lys-AMCA Chemical Structure

375822-19-8

Chemical Structure

  • D-Ala-Lys-AMCA
  • CAS No: 375822-19-8
    Formula: C21H28N4O6
    Molecular Weight: 432.47
  • IUPAC Name: N2-(D-alanyl)-N6-(2-(7-amino-4-methyl-2-oxo-2H-chromen-3-yl)acetyl)-L-lysine
  • InChIKey: JBMWHNASOBPJQQ-WBMJQRKESA-N
  • SMILES: NC1=CC=C(C(C)=C(CC(NCCCC[C@H](NC([C@@H](C)N)=O)C(O)=O)=O)C(O2)=O)C2=C1

Biological Activity: D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors[1][2].

Cat. No. Product Name Purity Description
HY-111956 D-Ala-Lys-AMCA D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors.

References

[1]. Gong Y, et al. Specific expression of proton-coupled oligopeptide transporter 1 in primary hepatocarcinoma-anovel strategy for tumor-targeted therapy. Oncol Lett. 2017 Oct;14(4):4158-4166. [Content Brief]
[2]. Groneberg DA, et al. Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1. Am J Physiol Gastrointest Liver Physiol. 2001 Sep;281(3):G697-704. [Content Brief]

Keywords:

D-Ala-Lys-AMCA