2. Immunology/Inflammation
  3. Interleukin Related
  4. 1327156-14-8

1327156-14-8

(S)-S007-1558 Chemical Structure

1327156-14-8

Chemical Structure

  • (S)-S007-1558
  • Synonym(s): GPVI antagonist 1
  • CAS No: 1327156-14-8
    Formula: C19H19N3O4S
    Molecular Weight: 385.44
  • IUPAC Name: (S)-2-((4-methoxyphenyl)sulfonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
  • InChIKey: KBVPHVCPUVDXOQ-SFHVURJKSA-N
  • SMILES: O=C([C@@H]1CC2=C(CN1S(=O)(C3=CC=C(OC)C=C3)=O)NC4=C2C=CC=C4)N

Biological Activity: (S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S)-S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM[1].

Cat. No. Product Name Purity Description
HY-144390 (S)-S007-1558 99.78% (S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S)-S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.

References

[1]. Holly Foster, et al. A Comparative Assessment Study of Known Small-molecule GPVI Modulators. ACS Med Chem Lett. 2022 Jan 20;13(2):171-181. [Content Brief]

Keywords:

(S)-S007-1558