2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. 1610414-00-0

1610414-00-0

EC1167 Chemical Structure

1610414-00-0

Chemical Structure

  • EC1167
  • CAS No: 1610414-00-0
    Formula: C33H45N7O17S
    Molecular Weight: 843.81
  • IUPAC Name: (9S,13S)-1-(4-(2-(((S)-3-carboxy-1-(((S)-3-carboxy-1-(((R)-1-carboxy-2-mercaptoethyl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)amino)-2-oxoethyl)phenyl)-3,11-dioxo-2,4,10,12-tetraazapentadecane-9,13,15-tricarboxylic acid
  • InChIKey: NAFZHTBVPLIASG-YFNVTMOMSA-N
  • SMILES: SC[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(O)=O)NC(CC1=CC=C(CNC(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)C=C1)=O)=O)=O

Biological Activity: EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].

Cat. No. Product Name Purity Description
HY-128938 EC1167 EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC).

References

[1]. Leamon CP, et al. Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate. Bioconjug Chem. 2019 Jun 19;30(6):1805-1813. [Content Brief]

Keywords:

EC1167