2. Autophagy
  3. Atg8/LC3
  4. 2471970-60-0

2471970-60-0

PROTAC Bcl-xL degrader-3 Chemical Structure

2471970-60-0

Chemical Structure

  • PROTAC Bcl-xL degrader-3
  • CAS No: 2471970-60-0
    Formula: C82H105ClF3N11O11S4
    Molecular Weight: 1641.49
  • IUPAC Name: (2S,4R)-1-((S)-2-(8-(4-(((R)-4'-chloro-4-methyl-6-((4-(4-(((4-(((R)-4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)carbamoyl)phenyl)piperazin-1-yl)methyl)-2,3,4,5-tetrahydro-[1,1'-biphenyl]-4-yl)methyl)piperazin-
  • InChIKey: KQEMZZJSHJCPSI-RYFXIQSLSA-N
  • SMILES: O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCCCCCC(N(CC4)CCN4C[C@@](C)(C5)CCC(C6=CC=C(C=C6)Cl)=C5CN7CCN(C8=CC=C(C=C8)C(NS(=O)(C9=CC(S(C(F)(F)F)(=O)=O)=C(C=C9)N[C@@H](CSC%10=CC=CC=C%10)CCN%11CCOCC%11)=O)=O)CC7)=O)=O

Biological Activity: PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader (WO2020163823A2, compound 44)[1].

Cat. No. Product Name Purity Description
HY-132997 PROTAC Bcl-xL degrader-3 PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader (WO2020163823A2, compound 44).

Keywords:

PROTAC Bcl-xL degrader-3