2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. 1628574-50-4

1628574-50-4

c-Fms-IN-9 Chemical Structure

1628574-50-4

Chemical Structure

  • c-Fms-IN-9
  • CAS No: 1628574-50-4
    Formula: C21H23N7O2
    Molecular Weight: 405.45
  • IUPAC Name: 5-(tert-butyl)-2-(6-methyl-5-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)-1,2-dihydro-3H-1,2,4-triazol-3-one
  • InChIKey: DKZTVZFTPXVEJW-UHFFFAOYSA-N
  • SMILES: O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1

Biological Activity: c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

Cat. No. Product Name Purity Description
HY-128680 c-Fms-IN-9 c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively.

References

[1]. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

Keywords:

c-Fms-IN-9