2. Anti-infection
  3. Bacterial
  4. 179479-03-9

179479-03-9

3’-O-Me-C(Bz)-2’-phosphoramidite Chemical Structure

179479-03-9

Chemical Structure

  • 3’-O-Me-C(Bz)-2’-phosphoramidite
  • CAS No: 179479-03-9
    Formula: C47H56N4O9P2
    Molecular Weight: 882.92
  • IUPAC Name: (2R,3R,4R,5R)-2-(4-benzamido-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) (diisopropylphosphanyl)phosphonite
  • InChIKey: AALHEPDXYGYRRZ-CATXLHIOSA-N
  • SMILES: O=C(NC(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OC)[C@H]3OP(OCCC#N)P(C(C)C)C(C)C

Biological Activity: 3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cat. No. Product Name Purity Description
HY-154481 3’-O-Me-C(Bz)-2’-phosphoramidite 3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Keywords:

3’-O-Me-C(Bz)-2’-phosphoramidite