2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. 1708103-69-8

1708103-69-8

ARTD10/PARP10-IN-2 Chemical Structure

1708103-69-8

Chemical Structure

  • ARTD10/PARP10-IN-2
  • CAS No: 1708103-69-8
    Formula: C12H13N3O3
    Molecular Weight: 247.25
  • IUPAC Name: N1-(3-carbamoylphenyl)-N4-methylmaleamide
  • InChIKey: FYQRBLGGKLIYRQ-WAYWQWQTSA-N
  • SMILES: CNC(/C=C\C(NC1=CC(C(N)=O)=CC=C1)=O)=O

Biological Activity: ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively[1].

Cat. No. Product Name Purity Description
HY-148710 ARTD10/PARP10-IN-2 ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively.

References

[1]. Ekblad T, et al. Towards small molecule inhibitors of mono-ADP-ribosyltransferases. Eur J Med Chem. 2015 May 5;95:546-51. [Content Brief]

Keywords:

ARTD10/PARP10-IN-2