1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. 172489-10-0

172489-10-0

KR-30450 Chemical Structure

172489-10-0

Chemical Structure

  • KR-30450
  • Synonym(s): SKP 450
  • CAS No: 172489-10-0
    Formula: C17H18N2O6
    Molecular Weight: 346.33
  • IUPAC Name: (R)-1-(2-(1,3-dioxolan-2-yl)-2-methyl-6-nitro-2H-chromen-4-yl)pyrrolidin-2-one
  • InChIKey: NJJPKIPOZSWUHV-QGZVFWFLSA-N
  • SMILES: O=C1N(C2=C[C@](C)(C3OCCO3)OC4=CC=C([N+]([O-])=O)C=C24)CCC1

Biological Activity: KR-30450 (SKP 450) is a potent K+ATP opener, and a potassium channel activator. KR-30450 exerts more potent cardioprotective effects than Lemakalim (HY-14255). KR-30450 significantly improves reperfusion cardiac function. KR-30450 significantly attenuates reperfusion contracture and lactate dehydrogenase release[1].

Cat. No. Product Name Purity Description
HY-19216 KR-30450 KR-30450 (SKP 450) is a potent K+ATP opener, and a potassium channel activator. KR-30450 exerts more potent cardioprotective effects than Lemakalim (HY-14255). KR-30450 significantly improves reperfusion cardiac function. KR-30450 significantly attenuates reperfusion contracture and lactate dehydrogenase release.

References

Keywords:

KR-30450