2. Anti-infection
  3. Parasite
  4. 1801444-69-8

1801444-69-8

RYL-552S Chemical Structure

1801444-69-8

Chemical Structure

  • RYL-552S
  • CAS No: 1801444-69-8
    Formula: C24H17F4NOS
    Molecular Weight: 443.46
  • IUPAC Name: 5-fluoro-3-methyl-2-(4-(4-((trifluoromethyl)thio)benzyl)phenyl)quinolin-4(1H)-one
  • InChIKey: FGVWBGSMONDTRE-UHFFFAOYSA-N
  • SMILES: O=C1C2=C(NC(C3=CC=C(CC4=CC=C(C=C4)SC(F)(F)F)C=C3)=C1C)C=CC=C2F

Biological Activity: RYL-552S kills drug-resistant strains of Plasmodium falciparum. RYL-552S can efficiently kill asexual blood-stage parasites in vitro[1].

Cat. No. Product Name Purity Description
HY-145912 RYL-552S 98.28% RYL-552S kills drug-resistant strains of Plasmodium falciparum. RYL-552S can efficiently kill asexual blood-stage parasites in vitro.

References

[1]. Yiqing Yang, et al. Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of <i>Plasmodium falciparum</i> (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria. J Med Chem. 2017 Mar 9;60(5):1994-2005. [Content Brief]

Keywords:

RYL-552S