2. Epigenetics
  3. Histone Methyltransferase
  4. 2131803-90-0

2131803-90-0

WYC-209 Chemical Structure

2131803-90-0

Chemical Structure

  • WYC-209
  • CAS No: 2131803-90-0
    Formula: C20H20N2O3S
    Molecular Weight: 368.45
  • IUPAC Name: ethyl 2-((4,4-dimethyl-1-oxidothiochroman-6-yl)ethynyl)pyrimidine-5-carboxylate
  • InChIKey: LLMDAYVUHYVJSS-UHFFFAOYSA-N
  • SMILES: O=C(C1=CN=C(C#CC2=CC=C3C(C(C)(C)CCS3=O)=C2)N=C1)OCC

Biological Activity: WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. WYC-209 induces apoptosis primarily via the caspase 3 pathway (IC50=0.19?μM for inmalignant murine melanoma TRCs), and has long-term effects with little toxicity[1].

Cat. No. Product Name Purity Description
HY-124136 WYC-209 98.68% WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. WYC-209 induces apoptosis primarily via the caspase 3 pathway (IC50=0.19?μM for inmalignant murine melanoma TRCs), and has long-term effects with little toxicity.

References

[1]. Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406. [Content Brief]

Keywords:

WYC-209